Seagate Nytro 3350 3.84TB
Enterprise SSD
Part number XS3840SE70045 · Nytro 3350 series · 2.5" SAS SSD. If your machine is listed below, this drive is officially supported — not a forum workaround.
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This is an SSD — an excellent cold copy for the off-site slot of a 3-2-1 plan: fast sequential transfer, silent, no moving parts to degrade on the shelf. The one catch is charge retention: a powered-off NVMe/SATA SSD slowly loses charge (weeks to months), which matters for a copy that sits unplugged. Keep the offline copy plugged in for a few hours once a month, or keep the 3-2-1 'other' copy on spinning media instead. Pair it with a scheduled backup job — see the backup software encyclopedia (Veeam, Duplicati, Hyper Backup) and the 3-2-1 rule.
Compatibility verdict
It appears on the official compatibility lists of 4 machines and series — 4 Synology. This is a Enterprise-class drive: rated for heavier sustained workloads than desktop drives. It is a strong pick for a NAS running 24/7, large-array rebuilds or camera workloads, and enterprise lines are also the drives most widely listed across all five vendors' HCLs. No series-level recording rating is on file for this part number yet, so check CMR vs SMR on the exact model before buying for an array.
Compatible NAS models
Same-capacity alternatives
Other drives listed at 3.84 TB capacity, ranked by how many machines list them:
Quick answers
Is the XS3840SE70045 officially compatible with my NAS?
It appears on the official compatibility lists of 4 machines and series — 4 Synology. Every machine page linked below shows the vendor's own list entry, refreshed daily.
Is the XS3840SE70045 a good NAS drive?
This is a Enterprise-class drive: rated for heavier sustained workloads than desktop drives. It is a strong pick for a NAS running 24/7, large-array rebuilds or camera workloads, and enterprise lines are also the drives most widely listed across all five vendors' HCLs. No series-level recording rating is on file for this part number yet, so check CMR vs SMR on the exact model before buying for an array.
Can I use the XS3840SE70045 for a 3-2-1 cold backup copy?
This is an SSD — an excellent cold copy for the off-site slot of a 3-2-1 plan: fast sequential transfer, silent, no moving parts to degrade on the shelf. The one catch is charge retention: a powered-off NVMe/SATA SSD slowly loses charge (weeks to months), which matters for a copy that sits unplugged. Keep the offline copy plugged in for a few hours once a month, or keep the 3-2-1 'other' copy on spinning media instead. Pair it with a scheduled backup job — see the backup software encyclopedia (Veeam, Duplicati, Hyper Backup) and the 3-2-1 rule.
What are alternatives to the XS3840SE70045?
At the same capacity, the most widely listed alternatives are Synology SAT5200-3840G (103 machines), Synology SAT5210-3840G (92 machines), Micron MTFDDAK3T8TCB-1AR1ZABYY (86 machines). The full ranked list is below.