NAS Drive Compatibility

Plextor M5S 256GB

Desktop SSD

Part number PX-0256M5S · M5S series · 2.5" SATA SSD. If your machine is listed below, this drive is officially supported — not a forum workaround.

M5S2.5" SATA SSD

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73
Compatible NAS models
73 Syn · 0 QNAP · 0 Asus · 0 TM
By vendor
256 GB
Listed capacity
Plextor
Manufacturer
Strong pick as a cold copy

This is an SSD — an excellent cold copy for the off-site slot of a 3-2-1 plan: fast sequential transfer, silent, no moving parts to degrade on the shelf. The one catch is charge retention: a powered-off NVMe/SATA SSD slowly loses charge (weeks to months), which matters for a copy that sits unplugged. Keep the offline copy plugged in for a few hours once a month, or keep the 3-2-1 'other' copy on spinning media instead. Pair it with a scheduled backup job — see the backup software encyclopedia (Veeam, Duplicati, Hyper Backup) and the 3-2-1 rule.

Compatibility verdict

It appears on the official compatibility lists of 73 machines and series — 73 Synology. Check the class badge above: drives tagged NAS or Enterprise are built for 24/7 multi-bay operation. Desktop-class drives often lack vibration resistance and are usually absent from vendor HCLs. No series-level recording rating is on file for this part number yet, so check CMR vs SMR on the exact model before buying for an array.

Compatible NAS models

Synology DS1010+5-bay See its full HCL → Synology DS110+1-bay See its full HCL → Synology DS110j1-bay See its full HCL → Synology DS1111-bay See its full HCL → Synology DS1121-bay See its full HCL → Synology DS112+1-bay See its full HCL → Synology DS112j1-bay See its full HCL → Synology DS1141-bay See its full HCL → Synology DS115j1-bay See its full HCL → Synology DS1511+5-bay See its full HCL → Synology DS1512+5-bay See its full HCL → Synology DS1513+5-bay See its full HCL → Synology DS1812+8-bay See its full HCL → Synology DS1813+8-bay See its full HCL → Synology DS2112-bay See its full HCL → Synology DS211+2-bay See its full HCL → Synology DS2122-bay See its full HCL → Synology DS212+2-bay See its full HCL → Synology DS212j2-bay See its full HCL → Synology DS2132-bay See its full HCL → Synology DS213+2-bay See its full HCL → Synology DS213air2-bay See its full HCL → Synology DS213j2-bay See its full HCL → Synology DS2142-bay See its full HCL → Synology DS214+2-bay See its full HCL → Synology DS214play2-bay See its full HCL → Synology DS214se2-bay See its full HCL → Synology DS216se2-bay See its full HCL → Synology DS2411+12-bay See its full HCL → Synology DS2413+12-bay See its full HCL → Synology DS3611xs12-bay See its full HCL → Synology DS3612xs12-bay See its full HCL → Synology DS4104-bay See its full HCL → Synology DS410j4-bay See its full HCL → Synology DS4114-bay See its full HCL → Synology DS411+4-bay See its full HCL → Synology DS411+II4-bay See its full HCL → Synology DS411j4-bay See its full HCL → Synology DS411slim4-bay See its full HCL → Synology DS412+4-bay See its full HCL → Synology DS4134-bay See its full HCL → Synology DS413j4-bay See its full HCL → Synology DS4144-bay See its full HCL → Synology DS415play4-bay See its full HCL → Synology DS710+7-bay See its full HCL → Synology DS712+7-bay See its full HCL → Synology DS713+7-bay See its full HCL → Synology RS10613xs+ See its full HCL → Synology RS212 See its full HCL → Synology RS214 See its full HCL → Synology RS2211+ See its full HCL → Synology RS2211RP+ See its full HCL → Synology RS2212+ See its full HCL → Synology RS2212RP+ See its full HCL → Synology RS2414+ See its full HCL → Synology RS2414RP+ See its full HCL → Synology RS3411RPxs See its full HCL → Synology RS3411xs See its full HCL → Synology RS3412RPxs See its full HCL → Synology RS3412xs See its full HCL → Synology RS3413xs+ See its full HCL → Synology RS3614xs+ See its full HCL → Synology RS3617xs See its full HCL → Synology RS411 See its full HCL → Synology RS810+ See its full HCL → Synology RS810RP+ See its full HCL → Synology RS812 See its full HCL → Synology RS812+ See its full HCL → Synology RS812RP+ See its full HCL → Synology RS814 See its full HCL → Synology RS814+ See its full HCL → Synology RS814RP+ See its full HCL → Synology RS815 See its full HCL →

Same-capacity alternatives

Other drives listed at 256 GB capacity, ranked by how many machines list them:

Micron MTFDDAK256MBF 123 machines · M600 Micron MTFDDAK256MAY 114 machines · M550 Crucial CT256M550SSD1 114 machines · M550 Transcend TS256GSSD370S 107 machines · SSD370S Samsung MZ-7PD256 91 machines · 840 Pro Kingston SKC400S37/256G 91 machines · SSDNow KC400 SanDisk SD6SB1M-256G 90 machines · X110 Micron MTFDDAK256TBN-1AR12 83 machines · 1100

Quick answers

Is the PX-0256M5S officially compatible with my NAS?

It appears on the official compatibility lists of 73 machines and series — 73 Synology. Every machine page linked below shows the vendor's own list entry, refreshed daily.

Is the PX-0256M5S a good NAS drive?

Check the class badge above: drives tagged NAS or Enterprise are built for 24/7 multi-bay operation. Desktop-class drives often lack vibration resistance and are usually absent from vendor HCLs. No series-level recording rating is on file for this part number yet, so check CMR vs SMR on the exact model before buying for an array.

Can I use the PX-0256M5S for a 3-2-1 cold backup copy?

This is an SSD — an excellent cold copy for the off-site slot of a 3-2-1 plan: fast sequential transfer, silent, no moving parts to degrade on the shelf. The one catch is charge retention: a powered-off NVMe/SATA SSD slowly loses charge (weeks to months), which matters for a copy that sits unplugged. Keep the offline copy plugged in for a few hours once a month, or keep the 3-2-1 'other' copy on spinning media instead. Pair it with a scheduled backup job — see the backup software encyclopedia (Veeam, Duplicati, Hyper Backup) and the 3-2-1 rule.

What are alternatives to the PX-0256M5S?

At the same capacity, the most widely listed alternatives are Micron MTFDDAK256MBF (123 machines), Micron MTFDDAK256MAY (114 machines), Crucial CT256M550SSD1 (114 machines). The full ranked list is below.